Serotonin depression

The Serotonin Theory of Depression

In its simplestfo rm, the serotonin deficiency theoryofdepression postulates that there is a net reduction in serotonin transmission in depressive illness. The pathophy siological change may result fr om two different mechanisms. Thejirst involves a decrease in serotonin (5-H T) availability which has the consequential tiffict ofcompensatory receptor up-regulation or supersensitiuity. The secon...

Serotonin, cytokines, p11, and depression.

F or at least four decades, the field of psychoimmunology has attracted numerous investigators based on diverse hints linking the immune system to emotional behavior. The administration of cytokines for the treatment of various diseases is often associated with depression, which frequently accompanies autoimmune disease. Now, in PNAS, Greengard and colleagues (1) report a specific molecular pat...

Brain Serotonin, Carbohydrate-craving, obesity and depression.

Serotonin-releasing brain neurons are unique in that the amount of neurotransmitter they release is normally controlled by food intake: Carbohydrate consumption--acting via insulin secretion and the "plasma tryptophan ratio"--increases serotonin release; protein intake lacks this effect. This ability of neurons to couple neuronal signaling properties to food consumption is a link in the feedbac...

Cortisol, serotonin and depression: all stressed out?

Serotonin Transporter Polymorphism in Relation to Depression

Correspondence to: Vjekoslav Peitl, MD Psychiatric Clinic Sestre Milosrdnice University Hospital Vinogradska Cesta 29, 10000 Zagreb, Croatia Tel/fax: +385 01 3787 742, email: [email protected] Copyright © 2015 KBCSM, Zagreb e-mail: [email protected] • www.http//hrcak.srce.hr/acoholism Abstract – Serotonin is regarded as one of the most important factors in modern psychiatry and...